Chinese scientists have confirmed that blood group affects people’s vulnerability to the coronavirus. The most vulnerable were the patients with the II blood group and the most stable — I group. Preprint with the results of scientific work published in the repository medRxiv.
Experts have compared the distribution of the different blood groups system AB0 from 2173 patients with COVID-19 from three hospitals in Wuhan and Shenzhen with distribution of blood groups in healthy people living in these regions. Among healthy people, the share of groups A, B, AB and 0 are 32.16, 24.90, 9.10 and 33.84% respectively, and for patients — 37.75, 26.42, 10.03 and 25.80 percent respectively. So people with a band And 1.2 times more likely to develop a coronavirus infection, and people with group 0 — 1.3 times less. Age and gender it does not affect the distribution.
The blood group on AB0 system are determined by the presence of genes A, b, 0 and so on, which encode different variants of the enzyme glycosyltransferase. She glycosylase (attaches the remnants of sugars) to a surface antigen of the erythrocyte — agglutinogen, creating specific agglutinogen A or B. In plasma could contain antibodies (α-, β-hemagglutinin) to antigens, which can cause agglutination of red blood cells, however, a person may present only one protein of each pair of agglutinogen A/α-hemagglutinin and agglutinogen In/β-hemagglutinin. This creates four possible combinations: 0 (blood group I) And (II), (III) and AB (IV).
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